Neck dissection for oral squamous cell carcinoma: our experience and a review of the literature
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:Rani Pooja
:Bhardwaj Yogesh/:Dass Praveen Kumar/:Gupta Manoj/:Malhotra Divye/:Ghezta Narottam Kumar
KMID : 0355620150410060299
Abstract
Objectives: This article describes our experience with neck dissection in 10 patients with oral squamous cell carcinoma.
Materials and Methods: Between January 2007 and October 2009, 10 patients underwent primary surgery for the treatment of squamous cell carcinoma of the oral cavity. For patients with N0 disease on clinical exam, selective neck dissection (SND [I-III]) was performed. In patients with palpable cervical metastases (N+), modifiedradical neck dissections were performed, except in one patient in whom SND (I-III) was performed. The histopathologic reports were reviewed to assess the surgical margins, the presence of extra-capsular spread, perineural invasion, and lymphatic invasion.
Results: On histopathologic examination, positive soft tissue margins were found in three patients, and regional lymph node metastases were present in fiveof the ten patients. Perineural invasion was noted in fivepatients, and extra nodal spread was found in four patients. Regional recurrence was seen in two patients and loco-regional recurrence plus distant metastasis to the tibia was observed in one patient. During the study period, three patients died. Seven patients remain free of disease to date.
Conclusion: Histopathological evaluation provides important and reliable information for disease staging, treatment planning, and prognosis. The philosophy of neck dissection is evolving rapidly with regard to the selectivity with which at-risk lymph node groups are removed. The sample size in the present study is small, thus, caution should be employed when interpreting these results.
키워드
Squamous cell carcinoma; Neck dissection; Selective neck dissection
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